It's still about ranges and mistakes. You don't necessarily need to tighten up, just try to make the best possible decision against their ranges, which will end up being weak in many spots because their mistake is that they call too much preflop and peel too many flops with weak hands.

They will end up getting to turns and rivers with weak ranges and you can barrel them off with your bluffs, or you can value bet thinly when you have it. (Don't worry too much about balance against fish. You can exploit their mistakes by manipulating sizing according to what you're trying to accomplish.)

Don't slowplay…get the money in early with your value hands (again, their mistake is seeing too many flops and calling too often with weak pairs and draws).

Also, try to familiarize yourself, through experience, with the standard actions and lines they take, which are pretty common and often really transparent. (For example, sizing bets according to hand strength.)

I have a live sweat series coming up soon that features a lot of Bovada. There should be several good spots on there.