Depends on how deep you are when heads-up play begins. If you're both somewhat shallow you need to basically play it out the way you would as if it were a 180 turbo – shove wide, call somewhat tight.

If you're deep I recommend min-raising every button and pot controlling in position. Don't keep calling his button opens out of position with weakish hands. Either 3 bet some times or fold. You're asking to bleed money left and right if you turn into a call station HU.