Fold pre-flop, call flop. Having a pretty hand is not by itself a reason to raise. What are you looking to accomplish with your flop raise?

You’re right that you shouldn’t be flatting only sets, but I think there are better hands for flatting than Axs. Also you shouldn’t be thinking of it as a “speculative hand” if by that you mean that you are mostly just trying to make a flush. Set-mining is an exception, but in general your strategy shouldn’t be built around playing passively trying to draw to a big hand and then get paid off when you get there.

Here’s a good way to think about constructing your range. So you know you want to flat a lot of PPs because you think set mining will be profitable. If your opponents knew this were your strategy, how could they react?

Well, they could c-bet you tons, especially on high card boards, because of how rarely you flop sets. Then when you do continue past the flop they could just give up. So how will you disincentivize them from doing these things?

You want hands that DO flop well on the kinds of flops that are bad for pocket pairs, meaning broadway cards. You also want hands that you can use as bluffs on the kinds of flops that are especially good for your PP range. Suited and connected big cards tends to make the best bluffing hands. So, you fill out your flatting range with a lot of suited broadways and large suited connectors.

Yes, suited Aces can also produce these kinds of hands, but they don’t do it as well. They don’t flop draws as often as suited connectors, and they don’t flop top pair as often as broadway hands.